Highlights
- Vicodin is a prescription opioid pain medication that combines hydrocodone and acetaminophen.
- Signs of addiction to Vicodin include weight loss, poor hygiene, and sleep issues, while overdose may lead to severe breathing problems, organ damage, and coma.
- An individual addicted to Vicodin may become dependent on it and experience withdrawal symptoms if they stop taking it.
- Treatment is available for individuals showing signs of Vicodin misuse or addiction in Wilmington, NC.
- EHG of NC provides treatment for opioid misuse, including Vicodin addiction.
- We proudly serve clients from Wilmington, across North Carolina, and nationwide. Professional care is available wherever you are coming from.
Vicodin is a prescription pain medication containing the opioid hydrocodone and acetaminophen 1. Someone who is at risk of addiction may show the following signs of Vicodin use before becoming addicted to the drug:
- Drastic changes in physical appearance
- Body fatigue and weakness
- Lung complications
- Heart issues
- Skin clamming
Worried about these signs and symptoms of Vicodin? Seek professional help at the EHG of NC to get a confidential appointment.

Is Vicodin Addictive?
Vicodin is a highly addictive narcotic pain-relieving drug and is classified as a Schedule II drug by the Drug Enforcement Administration (DEA) 2. Hydrocodone or Vicodin dependence can develop with repeated use of the drug, and the exact duration varies from person to person.
The primary active ingredients are 3:
| Drug Names | Dose (mg) |
| Hydrocodone Bitartrate (a semi-synthetic opioid) | 5 mg |
| Acetaminophen (Tylenol) | 500 mg |
What Are the 5 Visible Signs of Vicodin Use?
Vicodin is highly addictive, and a person using hydrocodone and Acetaminophen combined may show visible physical signs. However, after long-term use, Vicodin overdose results in serious complications.
Some of the common physical signs of Vicodin use (opioid addiction) are 4:
- Changes in physical appearance (weight loss)
- Neglecting personal hygiene
- Bloodshot eyes
- Sudden changes in eating habits
- Insomnia or Irregular sleeping patterns
What Are the Symptoms of Vicodin Use?
As per the FDA, overdose signs and Vicodin addiction symptoms may include 3:
- Respiratory depression
- Skeletal muscle flaccidity
- Cold and clammy skin
- Bradycardia
- Hypotension
- Fatal hepatic necrosis
- Renal tubular necrosis
- hypoglycemic coma
- Thrombocytopenia

Expert Review
How Will I Know If Someone Around Me Is Addicted To Vicodin?
Our Licensed Clinical Addiction Specialist says,
Self-assessment and recognizing the signs of Vicodin addiction in family members or others may help a person to seek timely help. Some signs on how to tell if an individual is addicted to the substance include:
- Finishes the prescription faster than it was intended
- Constantly complains about not having enough drugs
- Uses the drug through snorting or smoking
- Shows signs of euphoria
- Combines Vicodin with other substances
- Neglect commitments at work, home and school
Common Behavioral and Psychological Changes of Using Vicodin
After using Vicodin, individuals may have these common behavioral and psychological changes:
| Behavioral Changes | Psychological Changes |
| Changes in daily activities | Changes in mood or personality |
| Major shifts in social circles or less time spent with family | The onset of constant depression or anxiety |
| Secretive and concerning behavior | Acting delusional and having obsessive thoughts |
| Declining performance at college or work | Having a harmful self-image |
| Neglecting family obligations | Lack of motivation to do anything |
7 Common Side Effects of Vicodin Abuse
Medical Professionals in NC may prescribe Vicodin to treat patients’ pain. However, the Vicodin side effects are 5 6:
| Short-Term Effects Of Vicodin | Long-Term Effects Of Vicodin |
| Nausea | Substance Addiction |
| Vomiting | Liver Problems & Jaundice |
| Drowsiness & Dizziness | Anxiety & Depression |
| Confusion | Increased Pain Sensitivity |
| Slowed Breathing | Mood Changes & Irritability |
| Impaired Judgement | Memory Problems & Seizures |
| Loss Of Consciousness | Blurred Vision |
How To Recognize The Level of Vicodin Addiction?
As per ASAM DSM V criteria, there are 11 points to define opioid use disorders. The addiction severity depends on how many points a person meets. The current criterion is 7:
| Addiction Severity | Criteria Points Met |
| Mild Addiction | 2 – 3 symptoms |
| Moderate Addiction | 4 – 5 symptoms |
| Severe Addiction | 6+ symptoms |
Vicodin Overdose Statistics in North Carolina
- In 2017, Wilmington was at the very top of the list, with more than 11.6% of the population abusing opiates 8.
- From 2000 to 2020, the overall opioid death rate, including Vicodin or hydrocodone overdose, was more than 28,000 in North Carolina (NC) residents 9.
- The opioid dispensing rate was 44.5% in NC in 2024 10.
- Over 12 people lose their lives in North Carolina every day from drug overdoses, including opioids and fentanyl 11.
- Opioid overdose-related emergency department (ED) visits were nearly 2.88 million nationally 12.
How To Get Professional Vicodin Addiction Treatment?
Recent substance use statistics 3.20% population in North Carolina is using opioids. Seek professional help to break the addiction cycle and start your Vicodin addiction treatment with medical professionals.
Treatment teams may coordinate medication-assisted treatment when clinically appropriate:
Follow these 5 steps to get the right help:
- Contact at 910-335-9102 or fill out the online form.
- Get a complete substance abuse evaluation for Vicodin.
- Receive a confidential assessment and start your treatment in same-day rehab admission services, such as:
- Get psychotherapies like CBT, DBT, and EMDR to treat the underlying triggers of Vicodin use.
- After substance abuse treatment, individuals may enroll in a transitional living program to prevent relapse.
Empower Health Group of North Carolina welcomes people to travel to us from Mecklenburg, Guilford, Forsyth and nearby counties. We accept most commercial insurance providers and also offer self-pay monthly care options starting from $8,000.
Happy Words From a Client Who Received Our IOP Program Says,
“I was really worried about my overuse of prescription medication Vicodin. After searching for “IOP reddit” queries, someone suggested me to enroll in an intensive outpatient program for adults at EHG of NC for treatment.
I called the team and got into the IOP program in Wilmington, NC. After 2 months, I am feeling much better; the team helped me manage my moderate symptoms.”
Frequently Asked Questions Related To the Signs of Vicodin Abuse
People looking for Vicodin abuse symptoms and signs also ask questions, such as:
Can You Get Addicted To Vicodin After Only A Short Time?
Yes, Vicodin addiction can build up very quickly. As per Johns Hopkins Medicine, it may develop within a couple of weeks of use and varies from person to person 13.
Can You Overdose on Vicodin?
Vicodin is a dangerous narcotic, and taking too much may cause an overdose 14. The excessive toxin results in:
- Respiratory distress (slowed breathing rate)
- Causes organ failure or death
What Are The Consequences Of Getting High On Vicodin?
Getting high on Vicodin may cause short-term and long-term complications, including 4:
- Hypoxia
- Constipation
- Brain damage
- Respiratory issues
What Do People Most Commonly Associate With Vicodin?
Vicodin is most commonly associated with pain relief and relaxed effects (especially for moderate to severe pain) 15.
How Does Vicodin Make You Feel?
Opioids like Vicodin make a person feel relaxed and calm. The chemicals hydrocodone bitartrate and acetaminophen can affect brain regions involved in the perception of pleasure 16. When taken in high doses, it results in a “high feeling”.
How Is Vicodin Used And Abused?
Vicodin is commonly taken orally. Some individuals inject it directly into the bloodstream for an immediate high. The effects usually last for 4 to 6 hours, and present as 17:
- Pain relief
- Relaxation effects
- Sense of well-being
References
- https://www.ebsco.com/research-starters/health-and-medicine/vicodin
- https://www.dea.gov/drug-information/drug-scheduling
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/088058s027lbl.pdf
- https://nida.nih.gov/publications/drugfacts/prescription-opioids
- https://www.ncbi.nlm.nih.gov/books/NBK537288/
- https://www.mcieast.marines.mil/Portals/33/Documents/Safety/Abuse/Hydrocodone.pdf
- https://www.asam.org/docs/default-source/education-docs/dsm-5-dx-oud-8-28-2017.pdf
- https://www.northcarolinahealthnews.org/2017/07/27/four-north-carolina-cities-make-top-25-list-opioid-abuse/
- https://www.ncdhhs.gov/about/department-initiatives/overdose-epidemic
- https://www.cdc.gov/overdose-prevention/data-research/facts-stats/opioid-dispensing-rate-maps.html
- https://www.wral.com/story/nearly-12-people-die-each-day-in-nc-from-overdoses-state-data-shows/21027750/
- https://www.sciencedirect.com/science/article/abs/pii/S0376871621000636
- https://www.hopkinsmedicine.org/health/conditions-and-diseases/opioid-use-disorder
- https://ufhealth.org/conditions-and-treatments/hydrocodone-oxycodone-overdose
- https://www.sciencedirect.com/topics/nursing-and-health-professions/hydrocodone-bitartrate-plus-paracetamol
- https://www.reeve.uci.edu/news/chronic-pain-changes-your-brain-in-areas-important-for-reward-and-emotion
- https://www.mayoclinic.org/drugs-supplements/hydrocodone-and-acetaminophen-oral-route/description/drg-20074089
Medical Disclaimer:
EHG of NC aims to improve the quality of life for people struggling with substance use disorder and mental health issues. Our team of licensed medical professionals research, edit and review the content before publishing. However, this information is not intended to be a substitute for professional medical advice, diagnosis, or treatment. For medical advice, please consult your physicians or EHG of NC's qualified staff.
